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Environmental Chemicals That Deplete Male Testosterone

Endocrine-disrupting chemicals (EDCs) are problematic for the proper functioning of the hormone system. These chemicals are found in commonly used products like water bottles, plastics, cosmetics, canned food, fertilizers, toothpastes, clothes, soaps, paper, textiles, carpets, utensils, deodorants, bedding, and from various other products that wind up in the body. It is known that EDCs interfere with the synthesis and activity of sex hormones like testosterone. There is a link between an increase in several EDCs and declining sperm count and testosterone levels.

Bear in mind the following common toxins:

  • Phthalates, used in plastics, have been found in the urine of 75 percent of Americans.33 Phthalates disrupt testosterone development by interfering with the metabolism of cholesterol in the Leydig cells of the testes. Cholesterol is required to synthesize testosterone.
  • Bisphenol A (BPA) is a plasticizer found in the urine of the majority of Americans. BPA has been shown to disrupt testosterone synthesis by blocking LH receptors on Leydig cells.
  • Dioxins and PCB are EDCs that disrupt the hypothalamic-pituitary-thyroid axis, which regulates steroid production, thus decreasing testosterone. Dioxins are byproducts of industrial processes such as smelting, chlorine bleaching of paper pulp, and the manufacturing of some pesticides and herbicides. The majority of dioxins enter the body through the food chain, particularly meat and dairy products, fish, and shellfish. They build up in the fat tissues of humans and other animals.
  • Insecticides are frequently found in the urine of males. Research has shown that certain pesticides are linked to lowered testosterone levels. A study in the International Journal of Reproduction, Contraception, Obstetrics and Gynecology revealed that pesticides and insecticides considerably reduce serum testosterone and sperm levels.
  • Toxic metals are also an issue for testosterone deficiency. For instance, organic mercury is a common contaminant in our environment. Sources consist of fossil fuel emissions, the burning of medical waste, dental amalgams, vaccines, and incandescent lights. The primary type is methylmercury, which builds up in fish and is eaten by humans. Research has shown that mercury can alter the messaging system of the hypothalamic-pituitary-gonadal axis and impact reproductive function and circulating testosterone levels.

Avoid and Detoxify

The avoidance of endocrine disruptors is essential. This can be achieved through consuming purified water and organic foods and using "clean" cosmetics and personal care products. Also, routine detoxification support via exercise, sauna therapy, and also detoxifying nutraceuticals is recommended. Typical products I use with my patients include Glutathione Plus, Liver Wellness, and Inflam Fighter.