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The Incredible Impacts of Ergothioneine on Aging & Longevity

Most people have never heard of ergothioneine—yet the research around it is getting loud for one reason: it appears to be uniquely protective for the brain. This sulfur-containing antioxidant can cross the blood–brain barrier (a big deal), concentrate in brain tissue, and support key processes tied to cognitive aging.

In this video, Dr. Mark Stengler breaks down what ergothioneine is, why deficiency matters, and what studies suggest about the link between low blood levels and faster cognitive decline. He also covers how ergothioneine may protect mitochondria (your cells’ energy factories), reduce inflammation, and influence aging pathways—plus the most practical way to get more of it through food, especially ergothioneine-rich mushrooms like golden oyster.

If you’re serious about protecting memory, focus, and brain resilience as you age, this is one “under-the-radar” nutrient worth understanding.

CHAPTERS

00:00 – What is Ergothioneine?

00:18 – Powerful brain benefits

00:33 – Why your body can’t make it

00:44 – Antioxidant & anti-aging effects

01:00 – Protects brain cells and mitochondria

01:47 – Linked to better memory & cognition

02:33 – Low levels tied to brain decline

03:09 – How to get it from food

04:29 – Golden oyster mushroom benefits

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