
Most people have never heard of ergothioneine—yet the research around it is getting loud for one reason: it appears to be uniquely protective for the brain. This sulfur-containing antioxidant can cross the blood–brain barrier (a big deal), concentrate in brain tissue, and support key processes tied to cognitive aging.
In this video, Dr. Mark Stengler breaks down what ergothioneine is, why deficiency matters, and what studies suggest about the link between low blood levels and faster cognitive decline. He also covers how ergothioneine may protect mitochondria (your cells’ energy factories), reduce inflammation, and influence aging pathways—plus the most practical way to get more of it through food, especially ergothioneine-rich mushrooms like golden oyster.
If you’re serious about protecting memory, focus, and brain resilience as you age, this is one “under-the-radar” nutrient worth understanding.
CHAPTERS
00:00 – What is Ergothioneine?
00:18 – Powerful brain benefits
00:33 – Why your body can’t make it
00:44 – Antioxidant & anti-aging effects
01:00 – Protects brain cells and mitochondria
01:47 – Linked to better memory & cognition
02:33 – Low levels tied to brain decline
03:09 – How to get it from food
04:29 – Golden oyster mushroom benefits
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